Article

SARS-CoV-2 infection reduces Krüppel-Like Factor 2 in human lung autopsy

2021-01-18

Abstract excerpt

<h4>ABSTRACT</h4> Acute respiratory distress syndrome (ARDS) occurred in ~12% of hospitalized COVID-19 patients in a recent New York City cohort. Pulmonary endothelial dysfunction, characterized by increased expression of inflammatory genes and increased monolayer permeability, is a major component of ARDS. Vascular leak results in parenchymal accumulation of leukocytes, protein, and extravascular water, leading...

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Literature Corpus work: 7f0336df-4d8a-5353-bc50-641bbfadb0a6
DOI: 10.1101/2021.01.15.426691

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