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Genomic context of NTRK1/2/3 fusion-positive tumours from a large real-world population

20 Jul 2021

Abstract excerpt

Abstract Neurotrophic tropomyosin receptor kinase (NTRK) gene fusions are rare oncogenic drivers in solid tumours. This study aimed to interrogate a large real-world database of comprehensive genomic profiling data to describe the genomic landscape and prevalence of NTRK gene fusions. NTRK fusion-positive tumours were identified from the FoundationCORE® database of >295,000 cancer patients. We investigated the...

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PMID: 34285332
DOI: 10.1038/s41698-021-00206-y

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