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Real‐World Data Analysis of Genomic Alterations Detected by a Dual DNA – RNA Comprehensive Genomic Profiling Test

26 Mar 2025

Abstract excerpt

GenMineTOP, the first dual DNA-RNA comprehensive genomic profiling (CGP) test in Japan, was approved for reimbursement in 2023. To evaluate its clinical utility, we analyzed 1356 cases from the Center for Cancer Genomics and Advanced Therapeutics (C-CAT) database. Oncogenic genomic alterations were identified in 91.5% of cases. Somatic mutations were the most prevalent, followed by amplifications and fusion/exon...

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PMID: 40140952
DOI: 10.1111/cas.70071

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