Article

Pairing of Variable Heavy and Variable κ Chains in Individual Naive and Memory B Cells

1998-05-01

Abstract excerpt

Abstract A functional Ig consists of two heterodimers each of which is composed of a heavy and a light chain. Although there is increasing knowledge about the events that govern the rearrangement of the genes encoding each individual chain, only very limited information is available about the mechanisms governing the pairing of variable heavy (VH) and variable light (VL) chains. Using a single cell PCR, we were ab...

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Literature Corpus work: 7efb34e7-c95b-5a50-b80e-78dced792f05
DOI: 10.4049/jimmunol.160.10.4762

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