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Article

Using a heavy chain-loss hybridoma 26.4.1LL for studying the structural basis of immunoglobulin chain association.

Proceedings of the National Science Council, Republic of China. Part B, Life sciences - 1 Jul 2000

Yang C Y

Abstract excerpt

One of the mechanisms contributing to antibody diversity is created by the association of different heavy and light chains. The combinability of heavy and light chains has been studied previously in two systems: in vitro chain recombination and hybrid hybridoma. Here, a novel in vivo chain combination assay system involving a heavy chain-loss variant, 26.4.1LL, producing two kappa light chains (L(DEX) and L(MPC))...

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PMID: 10943942

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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