Article
Group IIA secreted phospholipase A <sub>2</sub> in human serum kills commensal but not clinical <i>Enterococcus faecium</i> isolates
2018-02-27
Abstract excerpt
Human innate immunity employs cellular and humoral mechanisms to facilitate rapid killing of invading bacteria. The direct killing of bacteria by human serum is mainly attributed to the activity of the complement system that forms pores in Gram-negative bacteria. Although Gram-positive bacteria are considered resistant to serum killing, we here uncover that normal human serum effectively kills Enterococcus faeciu...
Topics
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- Antibiotic Resistance in Bacteria
- Antimicrobial Resistance in Staphylococcus
- Burkholderia infections and melioidosis
- Infective Endocarditis Diagnosis and Management
- Neonatal and Maternal Infections
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Oral microbiology and periodontitis research
- Streptococcal Infections and Treatments
Identifiers and source
- Literature Corpus work
- 7ea48df6-9342-5108-809b-c09bae7c53b9
- DOI
- 10.1101/272617
