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<i>Bacteroidales</i> Secreted Antimicrobial Proteins Target Surface Molecules Necessary for Gut Colonization and Mediate Competition <i>In Vivo</i>

24 Aug 2016

Abstract excerpt

UNLABELLED: We recently showed that human gut Bacteroidales species secrete antimicrobial proteins (BSAPs), and we characterized in vitro the first such BSAP produced by Bacteroides fragilis In this study, we identified a second potent BSAP produced by the ubiquitous and abundant human gut species Bacteroides uniformis The two BSAPs contain a membrane attack complex/perforin (MACPF) domain but share very little...

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Identifiers

PMID: 27555309
DOI: 10.1128/mbio.01055-16

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