Article

Spatial and Temporal Expression of High Mobility Group Nucleosome-Binding (HMGN) Genes in Brain Areas Associated With Cognition in Individuals With Down Syndrome

2021-08-11

Abstract excerpt

<h4>Background: </h4> DNA methylation and histone posttranslational modifications are epigenetics processes which contribute to neurophenotype of Down Syndrome (DS). Previous reports present strong evidence that nonhistone High mobility group N proteins (HMGN) are epigenetic regulators. They play important functions in several process to maintain the brain homeostasis. We aimed to analyze the differential expressi...

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Literature Corpus work: 7e7c1ee3-b086-56ad-a60c-6d7f3f3b4e2e
DOI: 10.21203/rs.3.rs-784407/v1

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