Article

Targeting wild type NTRK decreases brain metastases of lung cancers non-driven by NTRK fusions

2026-03-20

Abstract excerpt

<h4>ABSTRACT</h4> The central nervous system (CNS) is a common site of metastatic spread for both non-small cell and small cell lung cancer, yet the therapeutic strategies to prevent and decrease lung cancer brain metastases remain limited. Tyrosine kinase inhibitors have shown promising results in increasing the overall response in brain metastases, owing to their brain penetrance and increased effectiveness; ho...

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Literature Corpus work: 7e63218c-6f2c-55c8-994f-1de2144fb204
DOI: 10.64898/2026.03.18.711213

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