Article

Bone marrow-on-a-chip: Emulating the human bone marrow

2018-11-18

Abstract excerpt

Multipotent hematopoietic stem and progenitor cells HSPC reside in specialized stem cell niches within the bone marrow, that provide a suitable microenvironment for lifelong maintenance of the stem cells. Meaningful in vitro models recapitulating the in vivo stem cell niche biology can be employed for both basic research as well as for applied sciences and represent a powerful tool to reduce animal tests in precli...

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Literature Corpus work: 7e089c0b-571f-522d-9abe-45b29bbff7d2
DOI: 10.1101/469528

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