Article
Manufacturing a Bone Marrow-On-A-Chip Using Maskless Photolithography.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2021
Souquet Benoit, Opitz Matthieu, Vianay Benoit, Brunet Stéphane, Théry Manuel
Abstract excerpt
The bone marrow (BM) is a complex microenvironment in which hematopoietic stem and progenitor cells (HSPCs) interact with multiple cell types that regulate their quiescence, growth, and differentiation. These cells constitute local niches where HSPCs are confined and subjected to specific set of physical and biochemical cues. Endothelial cells forming the walls of blood capillaries have been shown to establish a...
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