Article
FORGEdb: a tool for identifying candidate functional variants and uncovering target genes and mechanisms for complex diseases
2022-11-16
Abstract excerpt
The majority of disease-associated variants identified through genome-wide association studies (GWAS) are located outside of protein-coding regions and are overrepresented in sequences that regulate gene expression. Prioritizing candidate regulatory variants and potential biological mechanisms for further functional experiments, such as genome editing, can be challenging, especially in regions with a high number o...
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Identifiers and source
- Literature Corpus work
- 7df65483-8a40-5ea1-9fb4-b4103f277739
- DOI
- 10.1101/2022.11.14.516365