Article

Hetero-antagonism of avibactam and sulbactam with cefiderocol in carbapenem-resistant <i>Acinetobacter</i> spp

2024-03-06

Abstract excerpt

The emergence of Gram-negative bacteria resistant to multiple antibiotics, particularly carbapenem-resistant (CR) Acinetobacter strains, poses a significant threat globally. Despite efforts to develop new antimicrobial therapies, limited progress has been made, with only two drugs—cefiderocol and sulbactam-durlobactam—showing promise for CR- Acinetobacter infections. Cefiderocol, a siderophore cephalosporin, dem...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 38319356-0c5e-5512-a869-434d06807b2a
DOI: 10.1101/2024.03.04.583376

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Hetero-antagonism of avibactam and sulbactam with cefiderocol in carbapenem-resistant <i>Acinetobacter</i> sppDOI 10.1101/2024.03.04.583376Read

Synergistic cefiderocol-containing antibiotic combinations active against highly drug-resistant <i>Acinetobacter baumannii</i> patient isolates with diverse resistance mechanismsSemantic proximity Read

Epidemiology and Mechanisms of Ceftazidime–Avibactam Resistance in Gram-Negative BacteriaSemantic proximity Read

Carbapenem Resistance in Acinetobacter baumannii: Mechanisms, Therapeutics, and InnovationsSemantic proximity Read

Synergistic Activity of Cefiderocol in Combination with Avibactam, Sulbactam or Tazobactam against Carbapenem-Resistant Gram-Negative BacteriaSemantic proximity Read

Cefiderocol in Combating Carbapenem-Resistant Acinetobacter baumannii: Action and ResistanceSemantic proximity Read

Molecular mechanisms underlying bacterial resistance to ceftazidime/avibactamSemantic proximity Read

In Vitro Activity of Cefiderocol against a Global Collection of Carbapenem-Resistant Acinetobacter baumannii IsolatesSemantic proximity Read

Imipenem Resistance: A Clarion Call to Antibiotic StewardshipSemantic proximity Read

Characterization of Cefiderocol Heteroresistance in Carbapenem-Resistant Acinetobacter Baumannii (CRAB) Following Exposure to Human Pleural Fluid (HPF)Semantic proximity Read

Resistance to ceftazidime–avibactam and underlying mechanismsSemantic proximity Read

Salvage therapy with sulbactam/durlobactam against cefiderocol-resistant Acinetobacter baumannii in a critically ill burn patient: clinical challenges and molecular characterizationSemantic proximity Read

Antibiotic resistance of pathogenic Acinetobacter species and emerging combination therapySemantic proximity Read