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Article

Rational design of chemically responsive cytokines for cancer immunotherapy

2025-09-21

Abstract excerpt

Cytokines are key signal mediators of the immune system, playing essential roles in regulating central immunological processes. Despite their unique ability to modulate the immune system, the translation of cytokine-based therapies to the clinic has been significantly hindered by severe toxicities resulting from the pleiotropy and off-target effects of many cytokines. Here, we present a general strategy for the de...

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Literature Corpus work
7d865dfe-3337-5de1-bebe-2be1e088e5a2
DOI
10.1101/2025.09.18.677079
Open publication

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Rational design of chemically responsive cytokines for cancer immunotherapyDOI 10.1101/2025.09.18.677079
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