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Spatial transcriptomics identifies NGFR and EDIL3 as tumor budding-associated genes in triple-negative breast cancer

2026-06-10

Abstract excerpt

<title>Abstract</title> <p> Tumor budding (TB) is associated with aggressiveness and poor outcomes in triple-negative breast cancer (TNBC), yet its molecular mechanisms remain incompletely defined. This study aimed to identify TB-associated genes and delineate their functional and prognostic relevance in TNBC. Spatial bulk transcriptomic profiling was performed on 13 TNBC tissues stratified by TB levels. Differe...

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Literature Corpus work
7ce2df9d-50b1-5876-8d9d-e249f659be3b
DOI
10.21203/rs.3.rs-8789039/v1
Open publication

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Spatial transcriptomics identifies NGFR and EDIL3 as tumor budding-associated genes in triple-negative breast cancerDOI 10.21203/rs.3.rs-8789039/v1
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