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How long does it take to cue a <i>Pseudomonas aeruginosa</i> chronic infection phenotype in the lab? Insights from transcriptome analysis in a cystic fibrosis lung model

2022-06-30

Abstract excerpt

The opportunistic pathogen Pseudomonas aeruginosa forms biofilm infections in the lungs of people with the genetic condition cystic fibrosis (CF) that can persist for decades. There are numerous P. aeruginosa lifestyle changes associated with chronic biofilm infection cued by the CF lung environment. These include a loss of virulence, metabolic changes and increased antimicrobial tolerance. We have investigated...

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Literature Corpus work
af55c2d8-e38d-59fa-ab10-a27c71d88be3
DOI
10.1101/2022.06.30.498312
Open publication

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How long does it take to cue a <i>Pseudomonas aeruginosa</i> chronic infection phenotype in the lab? Insights from transcriptome analysis in a cystic fibrosis lung modelDOI 10.1101/2022.06.30.498312
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