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Cystic Fibrosis Sputum Supports Growth and Cues Key Aspects of <i>Pseudomonas aeruginosa</i> Physiology

19 Jul 2005

Abstract excerpt

The opportunistic human pathogen Pseudomonas aeruginosa causes persistent airway infections in patients with cystic fibrosis (CF). To establish these chronic infections, P. aeruginosa must grow and proliferate within the highly viscous sputum in the lungs of CF patients. In this study, we used Affymetrix GeneChip microarrays to investigate the physiology of P. aeruginosa grown using CF sputum as the sole source...

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Identifiers

PMID: 16030221
DOI: 10.1128/jb.187.15.5267-5277.2005

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