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Article

Apoptosis-Inducing TNF Superfamily Ligands for Cancer Therapy

27 Mar 2021

Abstract excerpt

Cancer is a complex disease with apoptosis evasion as one of its hallmarks; therefore, apoptosis induction in transformed cells seems a promising approach as a cancer treatment. TNF apoptosis-inducing ligands, which are naturally present in the body and possess tumoricidal activity, are attractive candidates. The most studied proteins are TNF-α, FasL, and TNF-related apoptosis-inducing ligand (TRAIL). Over the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 33801589
DOI: 10.3390/cancers13071543

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