Article

Adjuvant conditioning enhances neutrophil function while inducing a suppressive peritoneal macrophage phenotype

2025-04-19

Abstract excerpt

Adjuvants are widely used to boost the immune response during vaccination protocols. Our group has previously reported that repeated intraperitoneal administration of alum in mice, known as adjuvant conditioning (AC), creates an immunosuppressive environment that delays allogeneic graft rejection through NLRP3-dependent MDSC expansion. However, little is known about the effects of AC on the reprogramming of perito...

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Literature Corpus work: 7c949fed-2291-574b-b40f-416a010d3553
DOI: 10.1101/2025.04.15.648954

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