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Cardiorenal Effects of Angiotensin-converting enzyme inhibitors and Angiotensin receptor blockers in people underrepresented in trials: analysis of routinely collected data with validation against a target trial

2022-12-03

Abstract excerpt

<h4>Background</h4> Cardiovascular disease (CVD) is a leading cause of death globally. Angiotensin-converting enzyme inhibitors (ACEi) and angiotensin receptor blockers (ARB), compared in the ONTARGET trial, each prevent CVD. However, trial populations may not be representative of the general population. <h4>Methods</h4> Using trial replication methods within routine-care data, we explored replicability of the ONT...

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Literature Corpus work
7c62dcb9-ded0-5871-bac9-d8b13477b5d6
DOI
10.1101/2022.12.02.22282220
Open publication

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Cardiorenal Effects of Angiotensin-converting enzyme inhibitors and Angiotensin receptor blockers in people underrepresented in trials: analysis of routinely collected data with validation against a target trialDOI 10.1101/2022.12.02.22282220
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