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Comparative Effectiveness of Second-line Antihyperglycemic Agents for Cardiovascular Outcomes: A Large-scale, Multinational, Federated Analysis of the LEGEND-T2DM Study

2024-02-07

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> SGLT2 inhibitors (SGLT2is) and GLP-1 receptor agonists (GLP1-RAs) reduce major adverse cardiovascular events (MACE) in patients with type 2 diabetes mellitus (T2DM). However, their effectiveness relative to each other and other second-line antihyperglycemic agents is unknown, without any major ongoing head-to-head trials. <h4>Methods</h4> Across the LEGEND-T2DM network, we inc...

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Literature Corpus work
c27d7851-a5f9-599e-a293-b8df46e404cc
DOI
10.1101/2024.02.05.24302354
Open publication

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Comparative Effectiveness of Second-line Antihyperglycemic Agents for Cardiovascular Outcomes: A Large-scale, Multinational, Federated Analysis of the LEGEND-T2DM StudyDOI 10.1101/2024.02.05.24302354
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