Article

A Systematic Review of Representation in Clinical Trials for Transthyretin Associated Cardiac Amyloidosis: Where Demographics Diverge from Disease

2026-02-06

Abstract excerpt

<h4>Background</h4> Underrepresentation of minority groups in clinical trials worsens health disparities and reduces generalizability of results. Transthyretin-associated cardiac amyloidosis (ATTR), is a condition that disproportionately impacts some racial and ethnic groups yet the extent to which trial enrollment reflects disease burden remains unclear. Misalignment between disease prevalence and trial represen...

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Literature Corpus work: 1ed81696-56ff-53b0-bb9f-630d8298cc81
DOI: 10.64898/2026.02.04.26345614

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