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Replicating cardiovascular outcome trials of medications used to treat type 2 diabetes using real-world data: A systematic review of observational studies

2024-11-29

Abstract excerpt

<h4>Background: </h4> Cardiovascular outcome trials (CVOTs) are mandated by the U.S. Food and Drug Administration to assess the cardiovascular safety of new antidiabetic medications before entering the market. However, CVOTs often involve highly selective populations and results may not generalize to real-world settings. <h4>Methods:</h4> Our study aimed to synthesize observational studies to assess the generaliza...

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Literature Corpus work
36d7c5b4-4ccf-5a87-9069-e0f44b58db60
DOI
10.1101/2024.11.28.24317099
Open publication

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Replicating cardiovascular outcome trials of medications used to treat type 2 diabetes using real-world data: A systematic review of observational studiesDOI 10.1101/2024.11.28.24317099
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