Article

Pantothenate biosynthesis is critical for chronic infection by the neurotropic parasite <i>Toxoplasma gondii</i>

2021-10-04

Abstract excerpt

Coenzyme A (CoA) is an essential molecule acting in metabolism, post-translational modification, and regulation of gene expression. While all organisms synthesize CoA, many, including humans, are unable to produce its precursor, pantothenate. Intriguingly, like most plants, fungi and bacteria, parasites of the coccidian subgroup of Apicomplexa, including the human and animal pathogen Toxoplasma gondii , possess a...

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Literature Corpus work: 7c103182-03e5-55ea-aff6-f4d45e1d87b5
DOI: 10.1101/2021.10.04.462976

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