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Combining computational modeling and experimental library screening to affinity-mature VEEV-neutralizing antibody F5

2024-07-09

Abstract excerpt

<h4>ABSTRACT</h4> Engineered monoclonal antibodies (mAbs) have proven to be highly effective therapeutics in recent viral outbreaks due to their specificity and ability to provide immediate protection, regardless of immune status. However, despite technical advancements in the field, an ability to rapidly adapt or increase antibody affinity and by extension, therapeutic efficacy, has yet to be fully realized. We...

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Literature Corpus work
7be8a5fd-c08a-5246-b463-6212c696d4cc
DOI
10.1101/2024.07.08.602599
Open publication

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Combining computational modeling and experimental library screening to affinity-mature VEEV-neutralizing antibody F5DOI 10.1101/2024.07.08.602599
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