Article

Progesterone Receptor Isoform A But Not B Is Expressed in Endometriosis1

2000-08-01

Abstract excerpt

We previously demonstrated that 17β hydroxysteroid dehydrogenase type 2, the enzyme that inactivates estradiol to estrone, is expressed in luteal eutopic endometrium in response to progesterone but not in simultaneously biopsied peritoneal endometriotic tissue. This molecular evidence of progesterone resistance, together with the clinical observation of resistance of endometriosis to treatment with progestins, led...

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Identifiers and source

Literature Corpus work: 7bbc0361-6dc5-5eec-9b46-1217882dce4d
DOI: 10.1210/jcem.85.8.6739

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