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Systems-level longitudinal immune profiling reveals individualized immunotypes and genetic associations

2026-03-24

Abstract excerpt

The human immune system exhibits substantial inter-individual variation, yet how this variability is coordinated across the system and persists over time remains incompletely defined. Here, we integrated whole-genome sequencing with longitudinal multi-omics immune profiling in 101 healthy individuals followed over two years, combining mass cytometry-based immune cell profiling, PBMC transcriptomics, plasma proteom...

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Literature Corpus work
0202c22e-c9a4-5091-accb-699590ce3a62
DOI
10.64898/2026.03.21.713378
Open publication

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Systems-level longitudinal immune profiling reveals individualized immunotypes and genetic associationsDOI 10.64898/2026.03.21.713378
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