Article

Non-apoptotic caspase-dependent regulation of enteroblast quiescence in <i>Drosophila</i>

2019-07-20

Abstract excerpt

<h4>ABSTRACT</h4> Caspase malfunction in stem cells often instigates the appearance and progression of multiple types of cancer, including human colorectal cancer. However, the caspase-dependent regulation of intestinal stem cell properties remains poorly understood. Here, we demonstrate that Dronc , the Drosophila ortholog of caspase -9/2 in mammals, limits the proliferation of intestinal progenitor cells and...

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Literature Corpus work: 7b5cf62b-3ab3-5b0d-96cc-3729ceb2c53f
DOI: 10.1101/707380

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