Article

Depleting glioblastoma cells of very long-chain acyl-CoA synthetase 3 (ACSVL3) produces metabolic alterations in non-lipid pathways

2023-09-18

Abstract excerpt

<h4>ABSTRACT</h4> Knockout (KO) of the fatty acid-activation enzyme very long-chain acyl-CoA synthetase 3 (ACSVL3; SLC27A3) in U87MG glioblastoma cells reduced their malignant growth properties both in vitro and in xenografts. These U87-KO glioma cells grew at a slower rate, became adherence-dependent, and were less invasive than parental U87 cells. U87-KO cells produced fewer, slower-growing subcutaneous and int...

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Literature Corpus work: 7b494fc3-d3eb-5522-9163-685b82c8ce57
DOI: 10.1101/2023.09.18.558236

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Depleting glioblastoma cells of very long-chain acyl-CoA synthetase 3 (ACSVL3) produces metabolic alterations in non-lipid pathwaysDOI 10.1101/2023.09.18.558236Read

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