Article

Extracellular Histones Promote Calcium Phosphate-Dependent Calcification in Mouse Vascular Smooth Muscle Cells

2023-09-01

Abstract excerpt

<h4>Summary</h4> Vascular calcification, a major risk factor for cardiovascular events, is associated with a poor prognosis in chronic kidney disease (CKD) patients. This process is often associated with the transformation of vascular smooth muscle cells (VSMCs) into cells with osteoblast-like characteristics. Damage-associated molecular patterns (DAMPs), such as extracellular histones released from damaged or dy...

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Literature Corpus work: 7b4870af-f316-55d8-91de-cd40e6108638
DOI: 10.1101/2023.08.31.555403

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