Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Epigenetic modulation of vascular calcification: Looking for comprehending the role of sirt1 and histone acetylation in VSMC phenotypic transition.

Experimental cell research - 1 Nov 2024

Feltran Geórgia da Silva, Alves Dos Santos Emerson Araújo, de Camargo Andrade Amanda Fantini, Zambuzzi Willian Fernando, da Silva Rodrigo Augusto Foganholi

Abstract excerpt

In light of the complex origins of ectopic vascular calcification and its significant health implications, this study offers a comprehensive exploration of the molecular dynamics governing vascular smooth muscle cells (VSMCs). Focusing on epigenetic modulation, we investigate the transition from a contractile to a calcifying phenotype in VSMCs, with an emphasis on understanding the role of SIRT1. For this...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Acetylation
Share to DNA Methylation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Epigenesis, Genetic

Share to Histones

Share to Muscle, Smooth, Vascular

Share to Myocytes, Smooth Muscle

Share to Sirtuin 1

Share to Vascular Calcification

Source

Identifiers

PMID: 39476942
DOI: 10.1016/j.yexcr.2024.114311

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Epigenetic modulation of vascular calcification: Looking for comprehending the role of sirt1 and histone acetylation in VSMC phenotypic transition.PMID 39476942Read ↗

Roles of Histone Acetylation Modifiers and Other Epigenetic Regulators in Vascular CalcificationSemantic proximity Read ↗

Histone Lysine Methylation Modification and Its Role in Vascular CalcificationSemantic proximity Read ↗

An ncBAF-ETS2 Chromatin-Remodelling Axis Drives Vascular Smooth Muscle Cell Osteogenic Reprogramming in Vascular CalcificationSemantic proximity Read ↗

Role of smooth muscle cells in vascular calcification: implications in atherosclerosis and arterial stiffness.Semantic proximity Read ↗

The Epigenetic Landscape of Vascular Calcification: An Integrative PerspectiveSemantic proximity Read ↗

The Complex Interplay of Inflammation, Metabolism, Epigenetics, and Sex in Calcific Disease of the Aortic ValveSemantic proximity Read ↗

Molecular Mechanisms of Vascular Health: Insights From Vascular Aging and CalcificationSemantic proximity Read ↗

Vascular smooth muscle cell phenotypic plasticity and the regulation of vascular calcification.Semantic proximity Read ↗

Copper impedes calcification of human aortic vascular smooth muscle cells through inhibition of osteogenic transdifferentiation and promotion of extracellular matrix stabilitySemantic proximity Read ↗

Wnt Signaling in Vascular CalcificationSemantic proximity Read ↗

HDAC9 is implicated in atherosclerotic aortic calcification and affects vascular smooth muscle cell phenotype.Semantic proximity Read ↗

Sirtuin 1 modulation unlocks the therapeutic potential of sodium-glucose co-transporter 2 inhibitors (SGLT2i) in calcific aortic valve stenosisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.