Article

Improved diagnosis of inflammatory bowel disease and prediction and monitoring of response to anti-TNF alpha treatment based on measurement of signal transduction pathway activity

2022-05-16

Abstract excerpt

<h4>Objective</h4> Ulcerative colitis (UC) and Crohn’s disease (CD) are two subtypes of chronic inflammatory bowel disease (IBD). Differential diagnosis remains a challenge. Anti-TNFα treatment is an important treatment for IBD, yet resistance frequently occurs and cannot be predicted. Consequently, many patients receive ineffective therapy with potentially adverse effects. Novel assays are needed to improve diagn...

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Literature Corpus work: 7b441a2b-50c6-5105-9ac9-5ae2f4b7663f
DOI: 10.1101/2022.05.16.22275125

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