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Article

Genetic burden linked to founder effects in Saguenay-Lac-Saint-Jean illustrates the importance of genetic screening test availability.

Journal of medical genetics - 1 Oct 2021

Bchetnia Mbarka, Bouchard Luigi, Mathieu Jean, Campeau Philippe M, Morin Charles, Brisson Diane, Laberge Anne-Marie, Vézina Hélène, Gaudet Daniel, Laprise Catherine

Abstract excerpt

The Saguenay-Lac-Saint-Jean (SLSJ) region located in the province of Quebec was settled in the 19th century by pioneers issued from successive migration waves starting in France in the 17th century and continuing within Quebec until the beginning of the 20th century. The genetic structure of the SLSJ population is considered to be the product of a triple founder effect and is characterised by a higher prevalence...

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Identifiers

PMID: 33910931
DOI: 10.1136/jmedgenet-2021-107809
PMCID: PMC8479736

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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