Article
[Founder effects and genetic variability in Quebec].
Medecine sciences : M/S - 1 Nov 2007
Moreau Claudia, Vézina Hélène, Labuda Damian
Abstract excerpt
Knowledge of the genetic population structure lies at the heart of mapping studies aiming genes responsible for Mendelian and complex traits. The Quebec population, which is of mostly French descent, is considered an excellent model for such genetic epidemiological endeavours because it is a young founder population. Yet, the assessment of the founder effect has relied mostly on the observed distribution of...
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