A multi-ancestry genetic reference for the Quebec population.

doi:10.1038/s41467-026-68820-7

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Article

A multi-ancestry genetic reference for the Quebec population.

Nature communications - 3 Feb 2026

McClelland Peyton, Femerling Georgette, Laflamme Rose, Mejia-Garcia Alejandro, Sayahian Dehkordi Mohadese, Xiao Hongyu, Diaz-Papkovich Alex, Pelletier Justin, Grenier Jean-Christophe, Lo Ken Sin, Anderson-Trocmé Luke, Bellavance Justin, Chapdelaine Vincent, Gagnon Geneviève, De Mori Annelie, Martinez Gerardo, Mohler Kristen, de Malliard Thibault, Labbé Catherine, Labrecque Marjorie, Montpetit Alexandre, Spiegelman Dan, Rouleau Guy A, Théroux Jean-François, Zhou Hufeng, Girard Simon L, Hussin Julie G, Laberge Anne-Marie, Bhérer Claude, Tetreault Martine, Gagliano Taliun Sarah A, Taliun Daniel, Gravel Simon, Lettre Guillaume

Abstract excerpt

While international efforts have characterized genetic variation in millions of individuals, the interplay of environmental, social, cultural and genetic factors is poorly understood for most worldwide populations. The province of Quebec in Canada has been the site of numerous genetic studies, often focusing on Mendelian diseases in founder sub-populations. Here, we analyze genome-wide genotyped variation in...

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PMID: 41634041
DOI: 10.1038/s41467-026-68820-7
PMCID: PMC12868634

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