Article

Altered Surfactant Protein Gene Expression in Peripheral Blood Is Associated with COVID-19 Disease Severity

2025-05-07

Abstract excerpt

<h4>Background: </h4> /Objectives: Severe COVID-19 pneumonia causes alveolar type II cell damage and surfactant dysfunction, contributing to acute respiratory distress syndrome (ARDS). Surfactant proteins (SP-A, SP-B, SP-C, SP-D) are critical for reducing alveolar surface tension and defending against infection. We aimed to evaluate how surfactant protein gene expression affects COVID-19 severity Methods: Peripher...

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Literature Corpus work: 7b3a65b7-d339-53da-bcd3-be1e7fcb1966
DOI: 10.20944/preprints202505.0309.v1

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