Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Surfactant protein levels and genetic variants as biomarkers for COVID-19 severity in children.

American journal of physiology. Lung cellular and molecular physiology - 1 Mar 2025

Sicher Natalie, Aldrich Brycen, Zhang Shaoyi, Mazur Lauren, Juarez Susan, Lehman Erik, Liu Dajiang, Gandhi Chintan K

Abstract excerpt

Since its outbreak, the novel coronavirus (COVID-19) has significantly impacted the pediatric population. Pulmonary surfactant dysfunction has been linked to other respiratory diseases in children and COVID-19 in adults, but its role in COVID-19 severity remains unclear. We hypothesized that elevated surfactant protein (SP) levels and single nucleotide polymorphisms (SNPs) of SP genes are associated with severe...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biomarkers
Share to COVID-19

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Infant

Share to Pulmonary Surfactant-Associated Protein A

Share to Pulmonary Surfactant-Associated Protein D

Share to Pulmonary Surfactant-Associated Proteins

Share to SARS-CoV-2

Share to Severity of Illness Index

Source

Open in PubMed Open full text

Identifiers

PMID: 39832502
DOI: 10.1152/ajplung.00318.2024
PMCID: PMC12235610

Genes

SFTPC
SFTPA1
SFTPA2
SFTPB
SFTPD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Surfactant protein levels and genetic variants as biomarkers for COVID-19 severity in children.PMID 39832502Read ↗

Linking surfactant proteins and genetic variants to COVID-19 severitySemantic proximity Read ↗

The Impact of Surfactant Protein-D Gene Polymorphism on COVID-19 Clinical Outcomes.Semantic proximity Read ↗

Altered Surfactant Protein Gene Expression in Peripheral Blood Is Associated with COVID-19 Disease SeveritySemantic proximity Read ↗

Genetic variant associations of human SP-A and SP-D with acute and chronic lung injury.Semantic proximity Read ↗

Surfactant proteins as genetic determinants of multifactorial pulmonary diseases.Semantic proximity Read ↗

Association of SNP-SNP interactions of surfactant protein genes with severity of respiratory syncytial virus infection in children.Semantic proximity Read ↗

The lost chILD: a case report of delayed diagnosis of Surfactant Protein C Deficiency in a 15-year-old African maleSemantic proximity Read ↗

The surfactant protein B polymorphisms (rs7316 and rs1130866) and their correlation with disease progression of COVID-19.Semantic proximity Read ↗

Interstitial Lung Disease in Children: Rare Genetic Variants Beyond Surfactant Dysfunction.Semantic proximity Read ↗

Association of surfactant protein A2 with acute respiratory failure in children.Semantic proximity Read ↗

Genes Polymorphisms and Their Association with COVID-19 Severity in ChildrenSemantic proximity Read ↗

Genetic Polymorphisms of SP-A, SP-B, and SP-D and Risk of Respiratory Distress Syndrome in Preterm Neonates.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.