Article

Optineurin Gene Polymorpshism and Its Association With Glaucoma Onset

2022-03-07

Abstract excerpt

Glaucoma is a polygenic trait, and an irreversible visual impairment disorder caused by elevation of IOP (Intraocular Pressure), apoptotic death of the retinal Ganglion cells, excavation of optic nerve and ultimately vision loss if remain untreated. It is inherited in next generation in carrier families. In this study we aimed to identify the genetic polymorphism in OPTN gene and its association with glaucoma. Thr...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 7b2ca708-8589-5a12-878a-f6d42578aebb
DOI: 10.21203/rs.3.rs-1375307/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Optineurin Gene Polymorpshism and Its Association With Glaucoma OnsetDOI 10.21203/rs.3.rs-1375307/v1Read

OPTN gene: profile of patients with glaucoma from India.Semantic proximity Read

Current concepts on primary open-angle glaucoma genetics: a contribution to disease pathophysiology and future treatment.Semantic proximity Read

Meta-analysis of association between optineurin gene and primary open-angle glaucoma.Semantic proximity Read

Evaluation of Optineurin as a candidate gene in Indian patients with primary open angle glaucoma.Semantic proximity Read

A novel optineurin genetic mutation associated with open-angle glaucoma in a Chinese family.Semantic proximity Read

Analysis of optineurin (OPTN) gene mutations in subjects with and without glaucoma: the Blue Mountains Eye Study.Semantic proximity Read

Optineurin in primary open angle glaucoma.Semantic proximity Read

Adult-onset primary open-angle glaucoma caused by mutations in optineurin.Semantic proximity Read

Different optineurin mutation pattern in primary open-angle glaucoma.Semantic proximity Read

Analysis of rare variants and common haplotypes in the optineurin gene in Swedish glaucoma cases.Semantic proximity Read

[From gene to disease; primary open-angle glaucoma and three known genes: MYOC, CYP1B1 and OPTN].Semantic proximity Read

SNPs and interaction analyses of myocilin, optineurin, and apolipoprotein E in primary open angle glaucoma patients.Semantic proximity Read