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Article

Analysis of optineurin (OPTN) gene mutations in subjects with and without glaucoma: the Blue Mountains Eye Study.

Clinical & experimental ophthalmology - 1 Oct 2004

Baird Paul N, Richardson Andrea J, Craig Jamie E, Mackey David A, Rochtchina Elena, Mitchell Paul

Abstract excerpt

BACKGROUND: The optineurin (OPTN) gene has been reported to possess both causal as well as risk-associated alleles for open-angle glaucoma. However, these findings have so far only been reported in family and clinic based studies. The aim of this study was to investigate the spectrum of mutations and gene variants in OPTN that might be present in people with glaucoma from a population-based study, the Blue...

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Source

Identifiers

PMID: 15498064
DOI: 10.1111/j.1442-9071.2004.00886.x

Genes

OPTN

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Analysis of optineurin (OPTN) gene mutations in subjects with and without glaucoma: the Blue Mountains Eye Study.PMID 15498064Read ↗

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Molecular genetic analysis of optineurin gene for primary open-angle and normal tension glaucoma in the Japanese population.Semantic proximity Read ↗

Meta-analysis of association between optineurin gene and primary open-angle glaucoma.Semantic proximity Read ↗

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Different optineurin mutation pattern in primary open-angle glaucoma.Semantic proximity Read ↗

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