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Article

SNPs and interaction analyses of myocilin, optineurin, and apolipoprotein E in primary open angle glaucoma patients.

Molecular vision - 29 Aug 2005

Fan Bao Jian, Wang Dan Yi, Fan Dorothy Shu Ping, Tam Pancy Oi Sin, Lam Dennis Shun Chiu, Tham Clement Chuu Yang, Lam Ching Yan, Lau Tung Ching, Pang Chi Pui

Abstract excerpt

PURPOSE: To evaluate the association of myocilin (MYOC), optineurin (OPTN), and apolipoprotein E (APOE) genes and their interactions in primary open angle glaucoma (POAG). METHODS: A cohort of 400 unrelated POAG patients (294 high tension glaucoma, HTG, and 106 normal tension glaucoma, NTG) and 281 unrelated control subjects were recruited. All coding exons and splicing junctions in MYOC and OPTN were screened...

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Source

Identifiers

PMID: 16148883

Genes

MYOC
OPTN
APOE

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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