Article

Impact of variants and vaccination on nasal immunity across three waves of SARS-CoV-2

2024-05-29

Abstract excerpt

SARS-CoV-2 infection and COVID-19 disease vary with respect to viral variant and host vaccination status. However, how vaccines, emergent variants, and their intersection shift host responses in the human nasal mucosa remains uncharacterized. We and others have shown during the first SARS-CoV-2 wave that a muted nasal epithelial interferon response at the site of infection underlies severe COVID-19. We sought to f...

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Identifiers and source

Literature Corpus work: 7b162619-9f32-5524-8e9b-1fc72fcda91a
DOI: 10.1101/2024.05.29.596308

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