Article

Unraveling the Molecular Landscape of Uterine Fibroids, Insights into <i>HMGA2</i> and Stem Cell Involvement

2024-04-27

Abstract excerpt

Uterine fibroids are prevalent benign tumors in women that exhibit considerable heterogeneity in clinical presentation and molecular characteristics, necessitating a deeper understanding of their etiology and pathogenesis. HMGA2 overexpression has been associated with fibroid development, yet its precise role remains elusive. Mutations in fibroids are mutually exclusive and largely clonal, suggesting that tumors...

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Literature Corpus work: 7b034c4e-8d94-5a42-aee3-e78cad540279
DOI: 10.1101/2024.04.26.591351

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