Article

Tic-related behaviors in <i>Celsr3</i> mutant mice are contributed by alterations of striatal D <sub>3</sub> dopamine receptors

2023-12-08

Abstract excerpt

The gene CELSR3 (Cadherin EGF LAG Seven-pass-G-type Receptor 3) has been recently recognized as a high-confidence risk factor for Tourette syndrome (TS). Additionally, Celsr3 mutant mice have been reported to exhibit TS-related behaviors and increased dopamine release in the striatum. Building on these findings, we further characterized the neurobehavioral and molecular profile of Celsr3 mutant mice to understa...

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Literature Corpus work: 7af22ad9-f68c-5255-8643-0d5e05044494
DOI: 10.1101/2023.12.07.570669

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Tic-related behaviors in <i>Celsr3</i> mutant mice are contributed by alterations of striatal D <sub>3</sub> dopamine receptorsDOI 10.1101/2023.12.07.570669Read

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