Article
Genetic and epigenetic regulation of human lincRNA gene expression.
American journal of human genetics - 5 Dec 2013
Popadin Konstantin, Gutierrez-Arcelus Maria, Dermitzakis Emmanouil T, Antonarakis Stylianos E
Abstract excerpt
Large intergenic noncoding RNAs (lincRNAs) are still poorly functionally characterized. We analyzed the genetic and epigenetic regulation of human lincRNA expression in the GenCord collection by using three cell types from 195 unrelated European individuals. We detected a considerable number of cis expression quantitative trait loci (cis-eQTLs) and demonstrated that the genetic regulation of lincRNA expression is...
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