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Structure of a germline-like human antibody defines a neutralizing epitope on the SARS-CoV-2 spike NTD

2021-07-08

Abstract excerpt

Structural characterization of infection- and vaccination-elicited antibodies in complex with antigen provides insight into the evolutionary arms race between the host and the pathogen and informs rational vaccine immunogen design. We isolated a germline-like monoclonal antibody (mAb) from plasmablasts activated upon mRNA vaccination against SARS-CoV-2 and determined its structure in complex with the spike glycopr...

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Literature Corpus work
7ae8f3ca-310e-5bcb-a997-f96d125d334d
DOI
10.1101/2021.07.08.451649
Open publication

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Structure of a germline-like human antibody defines a neutralizing epitope on the SARS-CoV-2 spike NTDDOI 10.1101/2021.07.08.451649
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