Article

Accelerated amyloid deposition in SARS-CoV-2 infected mouse models of Alzheimer’s disease

2024-12-10

Abstract excerpt

Familial Alzheimer’s disease (AD) involving known AD causing genes accounts for a small fraction of cases, the vast majority are sporadic. Neuroinflammation, secondary to viral infection, has been suggested as an initiating or accelerating factor. In this work we tested the hypothesis that SARS-CoV-2 (SCV2) viral infection accelerates the development of AD pathology in mouse models of AD. We profiled transcriptomi...

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Literature Corpus work: 7a7217c9-eeec-5b9c-b443-6ca87b72bcb2
DOI: 10.1101/2024.12.09.627570

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