Article

Dipeptidyl Peptidase-4 Involved in Regulating Mitochondria Function in Cardiomyocytes through Nrf2 and PGC-1α Signaling

2020-06-04

Abstract excerpt

<h4>Background: </h4> Oxidative stress is an imbalance between the production of reactive oxygen species (ROS) and the detoxification ability of reactive intermediates. It will lead to mitochondrial damage and dysfunction, resulting in the dysfunction of bioenergetic control and loss of ATP production, which is contributed to the pathogenesis of cardiac diseases. Dipeptidyl peptidase-4 (DPP4) is a transmembrane gl...

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Literature Corpus work: 7a237f84-e90e-5954-90f8-657e3ec861df
DOI: 10.21203/rs.3.rs-30722/v1

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