Article

An oxide transport chain essential for balanced insulin signaling

2018-09-29

Abstract excerpt

<h4>Summary</h4> Patients with overnutrition, obesity, the atherometabolic syndrome, and type 2 diabetes mellitus exhibit imbalanced insulin action , also called pathway-selective insulin resistance. To control glycemia, they require hyperinsulinemia that then overdrives ERK and hepatic de-novo lipogenesis. We recently reported that NADPH oxidase-4 regulates balanced insulin action. Here, we show that NADPH oxid...

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Literature Corpus work: 1ed8e74b-997c-5c1b-9480-8e6c6c70f02d
DOI: 10.1101/430637

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