Cellular and Molecular Mechanisms of Metformin Action

Abstract excerpt

Metformin is a first-line therapy for the treatment of type 2 diabetes, due to its robust glucose-lowering effects, well-established safety profile, and relatively low cost. While metformin has been shown to have pleotropic effects on glucose metabolism, there is a general consensus that the major glucose-lowering effect in patients with type 2 diabetes is mostly mediated through inhibition of hepatic...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Diabetes Treatment and Management
• Share to Metabolism, Diabetes, and Cancer
• Share to Pancreatic function and diabetes