Article

Mito-nuclear Incompatibilities and Mitochondrial Replacement Therapy

2016-09-30

Abstract excerpt

Mitochondrial replacement therapy (MRT) is a human reproductive technology by which the mitochondria of a recipient’s eggs are effectively replaced by those of a donor, potentially eliminating harmful mitochondrial mutations carried by the recipient. However, concerns have been raised that MRT may lead to problems due to incompatibilities between the nuclear genome of the recipient and mitochondrial genome of the...

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Literature Corpus work: 79ce3a94-ed55-500f-a535-dd4f634a275e
DOI: 10.1101/078329

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